YourSaffron:Saffron: Uses, Side Effects, Dosage

By now you know that there are ample reasons as to why Saffron is the most expensive spice in the world. There are so many health benefits to using Saffron in your daily life. From boosting your anti-inflammatory intake and releasing anti-oxidative stress to making a wide range of meals and drinks taste amazing, Saffron really is a powerful spice! 

But what else is Saffron used for? There are more Saffron benefits than just flavour and better gut health. With properties that can kill cancer cells and improve your mood, the effects of Saffron can actually have a large impact on you and your daily life. 

Saffron has been proven to relieve symptoms of Alzheimer’s disease, premenstrual syndrome, depression and pregnancy just to name a few. In this article, we will discuss the medical uses of Saffron, the recommended dosage and the side effects that come with using Saffron to treat the aforementioned ailements.

Medical Uses and Recommended Dosage 

Alzheimer Disease

Saffron provides a natural way to promote brain function to a capacity that is so effective it can help delay and prevent symptoms of Alzheimer’s. Multiple studies show that Saffron truly does have anti-Alzheimer’s disease-fighting properties as it provides your body and brain with the right nutrients to stop memory problems and improve brain health. Saffron has the ability to halt memory loss at different stages of Alzheimer’s. In most cases, Saffron works about as well as the prescription drug donepezil (Aricept) but without any of the chemicals! 

Recommended dosage: 30 mg of saffron extract daily for 22 weeks.


Study after study has proven that Saffron is one of the most effective natural antidepressants anti-anxiety supplements. Medically reviewed and safer than prescription antidepressants, Saffron supplements provide natural support to alleviate symptoms of mild to moderate depression and anxiety. Research has found that patients who take Saffron have reduced symptoms within 4 weeks which is more effective than taking antidepressants alone. There are many negative side effects that come with taking prescription anti-depressants so it’s relieving for affected people to know that there are natural treatment options such as Saffron that are so effective at boosting serotonin production, improving sleep and reducing irritability that comes with depression. 

Recommended dosage: 30 mg of a saffron extract or 100 mg of saffron daily for up to 12 weeks.

Premenstrual Syndrome (PMS) and Menstrual Cramps (Dysmenorrhea)

The use of Saffron to treat PMS and menstrual cramps can have a significantly positive effect on your mental and physical state. The effects of using Saffron supplements to treat PMS come into effect after only two weeks and include an enhanced mood, ease of cramps and abdominal pain, improvement in skin complexion and better sleep. For best results, Saffron supplements should be taken a few days before your menstrual cycle begins and until completion. 

Recommended dosage for menstrual cramps (dysmenorrhea): 500 mg of a specific combination product containing saffron, celery seed and anise extracts taken three times a day for the first three days of menstruation ( source: Web MD).

Recommended dosage for premenstrual syndrome (PMS): 15 mg of Saffron extract twice daily.

Looking for somewhere to buy Saffron supplements? Browse our products here.

Side Effects

Saffron is safe to consume in food amounts but should not be taken as medicine for more than 26 weeks at a time when taken orally unless directed by your doctor. 

Some possible side effects include dry mouth, anxiety, agitation, drowsiness, low mood, sweating, nausea or vomiting, constipation or diarrhea, change in appetite, flushing, and headache. Allergic reactions can occur in some people.

Consuming high doses of Saffrib by mouth can be unsafe in incorrect dosages. Doses of 5 grams or more dried stigmas are considered high and can cause poisoning and doses of 12-20 grams can cause death. 

Special Precautions & Warnings:

Pregnancy and breast-feeding: Taking saffron by mouth in amounts larger than what is normally found in food is LIKELY UNSAFE. Larger amounts of saffron can make the uterus contract and might cause a miscarriage.

When pregnant or breastfeeding opt for food amounts of Saffron as there isn’t enough reliable information to know if saffron is safe to use when pregnant or breast-feeding. 

Bipolar disorder: As Saffron is able to affect moods there is a concern that it might trigger excitability and impulsive behaviour (mania) in people with bipolar disorder. Don’t use saffron if you have this condition.

Allergies to Lolium, Olea (includes olive), and Salsola plant species: People who are allergic to these plants might also be allergic to saffron.

Diabetes: Saffron might affect blood sugar levels. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use saffron.

Heart conditions: Saffron might affect how fast and how strong the heartbeats. Taking large amounts of saffron might worsen some heart conditions.

Low blood pressure: Saffron might lower blood pressure. Taking saffron might make blood pressure become too low in people with low blood pressure.